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Combined effect of additional resistance to breathing, hypoxia and hypercapnia on the female organism

The aim of the investigation at hand was to determine changes in some functional parameters of cardiopulmonary system, occurring as a result of a combined effect of an additional resistance to breathing, hypoxia and hypercapnia in the course of breathing through the Frolov's respiration training device.

Practically healthy women aged 38-39 were subjected to the examination. Studies of the external respiration function were performed with the "Masterlab" aparatus of the "ERICH JAGER" Company, that of gas exchange with the gas analyser of the named company. Parameters that were to be determined: respiration pattern - inhalation and exhalation time, respiratory act (cycle) duration. Tests under physical load were performed to determine gas exchange parameters, heartbeat frequency, general and biochemical blood analysis. Hemodynamics condition was assessed through tachooscillogram, recorded at the "HELLIGE" Company's apparatus. Combined effect of resistance to breathing, hypoxia and hypercapnia was simulated with the Frolov's inhalator. An additional resistance to breathing was created with the water obstruction of 35 mm Í2Î at the inhalation phase and 17 mm Í2Î at the exhalation phase. The gas analysis and oxygen blood saturation determination was performed before the training session, in the course of it and within an hour after it. Training sessions 20 min in duration were performed daily through three months.

Results.

As the practice of the respiratory exercises gained, the exhalation time gradually increased and nearing the end of the training course it showed 35 sec.



Figure 1. Exhalation capnogram. The ÑÎ2 content in the alveolar air (FetCO2) (change) dynamics exhibited by the tested patient K-n during the respiratory session (an additional resistance to breathing with hypoxia and hypercapnia). At the 1st day and, B - in two months's time

The hypoxic and hypercapnic effect grew in proportion with the exhalation time increase: Oxygen percentage in 1 liter volume was sinking down to 10%, while carbon dioxide percentage was rising up to 7% at the moment when the exhalation phase amounted to 30 sec.

The gain was a considerable decrease in respiration frequency from 16-18 to 6-8 per minute. This frequency diminished chiefly through the exhalation phase lengthening: the inhalation increased by 31.5%, the exhalation did so by 102.6%. Systole frequency lowered by 18%. The oxygen consumption restoration time after a uniform physical load decreased by 66.6%. The gas exchange parameters witnessed a considerable change (see Table).

The oxygen (FO2) utilization rate and ÑÎ2 content in the alveolar air evidenced increase at rest, as well as under a physical load. Thus, in this case, the adaptation changes became apparent already at rest, getting more pronounced still under a physical load. Our studies testify to the alveolar ventilation optimization along with respiratory and blood circulation function minimization as a result of the respiratory training.

The Institute for Physiology of The Siberian Branch of The Russian Academy of Sciences

2007/02/06

Kovtun L., Krivoshchekov S.


 
 

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